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传承人介绍



传承人介绍

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唐夏林


唐夏林,女,1993年04月出生,湖南娄底人,医学博士,湖北省中医院脑病科住院医师。从事中医脑病科研与临床工作,主要研究方向为中医药防治缺血性卒中临床及基础研究,主持省自然及省中管局课题各1项,参与国自然课题3项,发表SCI论文8篇。


学术兼职:


主持或参与项目:
主持课题:

1、湖北省中医药管理局, 2023~2024年度中医药青年人才项目, ZY2023Q001, 黄芪甲苷调控m6A结合蛋白YTHDF1介导小胶质细胞表型转化保护脑缺血再灌注损伤的机制研究, 在研, 主持;

2、湖北省科学技术厅, 省自然科学基金青年项目, 2022CFB923, 川芎嗪调控YTHDF1介导 m6A甲基化调节小胶质细胞功能在脑缺血再灌注损伤中的机制研究, 在研, 主持;


参与课题:

1、国家自然科学基金委员会, 面上项目, 81873262, 芎芪合剂对于调控NMDA受体-调节神经突触在脑缺血-再灌注损伤中的机制研究, 结题, 参与;

2、国家自然科学基金委员会, 青年科学基金项目, 81804038, 芎芪有效配伍介导PKC调控紧密连接信号通路对溶栓后出血转化的作用与机制研究,结题, 参与;

3、国家自然科学基金委员会, 青年科学基金项目, 31800727, RNA解螺旋酶DDX5在抗病毒天然免疫反应中的调控作用及分子机制研究,结题, 参与。


代表性论文及论著:

1、Xialing Tang#; Shanshan Xie#; Huajun Wang#; Yingbin Li#; Zhiyu Lai; Shuangxi Sun; Ruanhuan Pan; Yan Huang; Jun Cai.The combination of Astragalus membranaceus and ligustrazine mitigates cerebral ischemia‐reperfusion injury via regulating NR2B‐ERK/CREB signaling, Brain and Behavior, 2023, 13(2);

2、Pan, Ruihuan#; Tang, Xialin#; Wang, Huajun; Huang, Yan; Huang, Kai; Ling, Shanshan; Zhou,Mingchao; Cai, Jun; Chen, Hongxia.The Combination of Astragalus membranaceus and Ligustrazine Protects Against Thrombolysis-Induced Hemorrhagic Transformation Through PKC delta/Marcks Pathway in Cerebral Ischemia Rats, Cell Transplantation, 2020, 29: 0-0963689720946020    

3、Tang, Xialin; Wang, Huajun; Chen, Huihuan; Sun, Shuangxi; Chen, Hongxia; Pan, Ruihuan .Protective Effects of Astragalus Membranaceus and Ligustrazine on Rat Brain Microvascular Endothelial Cell Injury after Oxygen-Glucose Deprivation/Reoxygenation by Suppressing the PKCd/MARCKS Pathway, Combinatorial Chemistry & High Throughput Screening, 2021, 24(7): 947-956     

4、Wang, Hua-Jun#; Tang, Xia-Lin#; Huang, Gan; Li, Ying-Bin; Pan, Rui-Huan; Zhan, Jie; Wu, Ye-Kun; Liang, Jian-Feng; Bai, Xiao-xin; Cai, Jun. Long Non-Coding KCNQ1OT1 Promotes Oxygen-Glucose- Deprivation/Reoxygenation-Induced Neurons Injury Through Regulating MIR-153-3p/FOXO3 Axis, Journal of Stroke and Cerebrovascular Diseases, 2020, 29(10): 0-105126

5、Zheng, Linbo; Tang, Xialin; Lu, Minyi; Sun, Shuangxi; Xie, Shanshan; Cai, Jun; Zan, Jie .microRNA-421-3p prevents inflammatory response in cerebral ischemia/reperfusion injury through targeting m6A Reader YTHDF1 to inhibit p65 mRNA translation, International Immunopharmacology,2020, 88: 0-106937   

6、Zan Jie;Xu Ruixian ; Tang Xialin;Minyi Lu;Shanshan Xie;Jun Cai;Zhi Huang;Jinyang Zhang. RNA helicase DDX5 suppresses IFN-I antiviral innate immune response by interacting with PP2A-Cβto deactivate IRF3.EXPERIMENTAL CELL RESEARCH.2020;396 (2):112332.

7、Zhang, Xin-Chun; Gu, Ai-Ping; Zheng, Chun-Ye; Li, Ying-Bin; Liang,Hong-Feng; Wang, Hua-Jun; Tang, Xia-Lin; Bai, Xiao-Xin; Cai, Jun. YY1/LncRNA GAS5 complex aggravates cerebral ischemia/reperfusion injury through enhancing neuronal glycolysis, Neuropharmacology, 2019, 158: 0-107682

8、Ruihuan Pan;Mingchao Zhou;Yiping Zhong;Jingping Xie;Shanshan Ling;Xialin Tang, Yan Huang and Hongxia Chen. The combination of Astragalus membranaceus extract and ligustrazine to improve the inflammation in rats with thrombolytic cerebral ischemia[J]. International journal of immunopathology and pharmacology. 2019,33:2058738419869055


获得各类奖励及荣誉称号:

2020年获博士研究生国家奖学金;

2021年获校优秀毕业生;

2022年获湖北省中医院年度“科研工作先进个人”

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